TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2. TP0463518 also inhibits human PHD1/PHD3 with IC50s of 18 and 63 nM as well as monkey PHD2 with an IC50 value of 22 nM.
分子式
C20H18ClN3O6
分子量
431.83
CAS号
1558021-37-6
运输条件
Room temperature in continental US; may vary elsewhere.