| 生物活性 |
COTC is a bacterial metabolite that has been found in S. griseosporeus and has anticancer activity. It inhibits glyoxalase in the presence of glutathione (GSH) in a concentration- and time-dependent manner. COTC inhibits the proliferation of HeLa cells (IC50 = 18 µg/ml), as well as reduces tumor growth and improves survival in an Ehrlich murine spontaneous adenocarcinoma model.
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| 分子式 |
C11H14O6
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| 分子量 |
242.2
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| CAS号 |
57449-30-6
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| 运输条件 |
Room temperature in continental US; may vary elsewhere.
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| 储存方式 |
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纯度： >90%
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