| 生物活性 |
Ulefnersen sodium (ION363) is an Antisense Oligonucleotide (ASO) directed against the 6th intron of the fused-in sarcoma (FUS) transcript to silence FUS in a non-allele-specific manner. Ulefnersen sodium can reduce postnatal levels of FUS protein in the brain and spinal cord in disease-relevant mouse model of ALS-FUS , delaying motor neuron degeneration. Ulefnersen sodium can be used in the research of Amyotrophic Lateral Sclerosis (ALS) .
|
|---|---|
| 分子式 |
C230H302N68O126P19S13Na19
|
| 分子量 |
7060 (free acid)
|
| CAS号 |
2589926-27-0
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere.
|
| 储存方式 |
-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
|
纯度： 98%
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