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Metabolic Enzyme/Protease——Liposome

Liposomes (NPs typically 100–500 nm in diameter) are fabricated from the self-assembly of phospholipids, which consist of a polar phosphate head group and hydrophobic lipid tails. In aqueous environments, the hydrophobic tails self-orient, resulting in a spherical structure comprised of an aqueous core surrounded by a lipophilic bilayer membrane. Liposomes are both biocompatible and biodegradable (e.g., at certain pH and temperature), which can be controlled by modifying the lipid composition. Furthermore, liposomes are amenable to various modifications that improve their efficacy as drug delivery carriers.

Metabolic Enzyme/Protease——Liposome(10)

Cat. No. Product Name CAS No. Purity Chemical Structure
KP1387 5A2-SC8 1857341-90-2
KG12990 CIN-16645 1799316-64-5 >90%
KM31963 DSPE-PEG-Cy5, MW 2000 98%
KP18922 DSPE-PEG-SH, MW 1000

DSPE-PEG-SH (MW 1000) 是一种两亲性聚 PEG,可在水中形成脂质双层。该两性聚合物可在水溶液中形成脂质双分子层,可用于包埋活性分子,用于药物递送系统,如mRNA疫苗。

≥95%
KP18935 DSPE-PEG-SH, MW 10000

DSPE-PEG-SH,MW 10000 是一种马来酰亚胺反应性 PEG 脂质。该两亲性聚合物可在水中形成脂质双层,可用于制备脂质体,作为药物纳米载体,以输送 mRNA、DNA 或 siRNA。试剂级,仅供研究使用。

≥95%
KP18933 DSPE-PEG-SH, MW 2000 98%
KP18923 DSPE-PEG-SH, MW 5000

DSPE-PEG-SH, MW 5000 是聚 PEG 连接的 DSPE 分子。 脂质尾部允许在水中形成脂质双层,并可用于溶解疏水性药物,而亲水性核心可封装治疗剂,例如核酸(mRNA/DNA)、蛋白质或肽。 试剂级,仅供研究使用。

≥95%
KG13070 NT1-O14B 2739805-64-0 >95%
KP18033 TCL053

TCL053 是一种可电离的脂质,用于高效地将活性成分 (特别是核酸) 导入细胞。TCL053 能够与二棕榈酰磷脂酰胆碱 (DPPC)、聚乙二醇二肉豆蔻酰基甘油 (PEG-DMG) 和胆固醇,一起形成脂质纳米粒 (LNP),能够将 Cas9 mRNA 和 sgRNA 传递到骨骼肌中。

2361162-70-9 99%
KG12936 YSK05 1318793-78-0 >90%