| 生物活性 |
Pradefovir is a reverse transcriptase inhibitor potentially for treatment of chronic HBV infection. Pradefovir is also a liver-targeted prodrug of adefovir. After metabolic activation, Pradefovir was converted to PMEA (9-(2-phosphonylmethoxyethyl)adenine ) in human liver microsomes with a K(m) of 60 microM, a maximum rate of metabolism of 228 pmol/min/mg protein, and an intrinsic clearance of about 359 ml/min.
|
|---|---|
| 分子式 |
C17H19ClN5O4P
|
| 分子量 |
423.79
|
| CAS号 |
625095-60-5
|
| 中文名称 |
帕拉德福韦
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere.
|
| 储存方式 |
Store at -20˚C
|
纯度： ≥95%
关注我们
获得KKL MED 最新资讯
客服小K 
客服小K
Data Sheet