SARS-CoV-2-IN-14
(Synonyms:5-氯-N-(3-氯苯基)-2-羟基苯甲酰胺)
目录号 : KE9836
CAS No. : 22203-98-1
纯度 : ≥95%
SARS-CoV-2-IN-14 is a potent and oral inhibitor of SARS-CoV-2 (IC50:0.39 μM), which is an analogue of niclosamide. SARS-CoV-2-IN-14 was more stable than niclosamide in the determination of human plasma and liver S9 enzyme. Oral administration of SARS-CoV-2-IN-14 can improve its bioavailability and half-life.
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生物活性 |
SARS-CoV-2-IN-14 is a potent and oral inhibitor of SARS-CoV-2 (IC50:0.39 μM), which is an analogue of niclosamide. SARS-CoV-2-IN-14 was more stable than niclosamide in the determination of human plasma and liver S9 enzyme. Oral administration of SARS-CoV-2-IN-14 can improve its bioavailability and half-life.
|
分子式 |
C13H9Cl2NO2
|
分子量 |
282.12
|
CAS号 |
22203-98-1
|
中文名称 |
5-氯-N-(3-氯苯基)-2-羟基苯甲酰胺
|
运输条件 |
Room temperature in continental US; may vary elsewhere.
|
储存方式 |
Powder |
-20°C |
3 years |
|
4°C |
2 years |
In solvent |
-80°C |
6 months |
|
-20°C |
1 month |
|