Illudin M
目录号 : KM9032 CAS No. : 1146-04-9

Illudin M 是一种细胞毒性真菌倍半萜,可以从 Omphalotus olearius 蘑菇培养基中分离得到的。Illudin M 能使 DNA 烷基化。Illudin M 具有抗肿瘤活性。

规格 价格 是否有货 数量
1mg
In-stock

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生物活性

Illudin M is a cytotoxic fungal sesquiterpene that can be isolated from the culture medium of Omphalotus olearius mushrooms. Illudin M can alkylate DNA. Illudin M has anti-tumor activities.

体外研究

Illudin M (0.01-10 μM; 24-120 hours) shows cytotoxicity and induction of apoptosis in vitro.

Apoptosis Analysis

Cell Line: Panc-1 pancreatic carcinoma, HT-29 colon adenocarcinoma, non-malignant human foreskin fibroblasts (HFs)
Concentration: 0.01 μM, 1 μM, 10 μM
Incubation Time: 24 hours, 48 hours,72 hours, 96 hours, 120 hours
Result: Showed a comparable induction of apoptosis in the tumour cells (86% in Panc-1; 48% in HT-29), but an even greater one in the HF (89%).
分子式
C15H20O3
分子量
248.32
CAS号
1146-04-9
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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