KKL 顾客使用本产品发表的 1 篇科研文献

L-Aspartic acid is is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly.

L-Aspartic acid is shown to be a suitable prodrug for colon-specific drug deliverly. L-[H]Asp remaining in the brain at 5 min is increased by 206 and 178% by preadministration of 100 mM L-Aspartic acid and 100 mM L-Glu, respectively, whereas 100 mM D-Asp does not affect L-[H]Asp efflux transport. That value for L-[H]Glu at 20 min is increased by 145 and 156% by coadministration with 100 mM L-Aspartic acid and 100 mM L-Glu, respectively, but not by D-Asp. It is interesting that the apparent efflux rate of L-Aspartic acid across the BBB is sevenfold faster than that of L-Glu.

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