BIBF 1202是BIBF 1120的羧酸盐代谢物，抑制 VEGFR2 激酶的 IC50 值为62 nM。
| 生物活性 |
BIBF 1202 is the carboxylate metabolite of BIBF 1120 which inhibits VEGFR2 kinase with an IC50 of 62 nM. |
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| 体外研究 |
The major metabolic pathway for BIBF 1120 is methyl ester cleavage to BIBF 1202. Subsequently, the free carboxyl group of BIBF 1202 is glucuronidated to 1-O-acylglucuronide. |
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| 分子式 |
C30H31N5O4
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| 分子量 |
525.60
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| CAS号 |
894783-71-2
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 溶解性数据 |
In Vitro:
DMSO : ≥ 45 mg/mL (85.62 mM) * "≥" means soluble, but saturation unknown. 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
纯度： 98%
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