Cu(II)-Elesclomol 是Elesclomol和 Cu2+ (铜离子) 形成的络合物。Cu(II)-Elesclomol 也是 DNA 拓扑异构酶 I 的弱抑制剂。Cu(II)-Elesclomol 通过铜螯合诱导氧化应激和 DNA 损伤发挥抗癌作用。Cu(II)-Elesclomol 可抑制肿瘤细胞增殖，诱导细胞周期阻滞和凋亡 (apoptosis)。Cu(II)-Elesclomol 可用于肿瘤的研究。
| 生物活性 |
Cu(II)-Elesclomol is a complex formed by Elesclomol and Cu2+ (copper ions). Cu(II)-Elesclomol is also a weak inhibitor of DNA topoisomerase I. Cu(II)-Elesclomol exerts anticancer effects by inducing oxidative stress and DNA damage through copper chelation. Cu(II)-Elesclomol can inhibit tumor cell proliferation and induce cell cycle arrest and apoptosis. Cu(II)-Elesclomol can be used in the study of cancer. |
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| 分子式 |
C19H18CuN4O2S2
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| 分子量 |
462.05
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| CAS号 |
1224195-72-5
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 溶解性数据 |
In Vitro:
DMSO: 6.67 mg/mL (14.44 mM; 超声助溶 (<80°C);) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
纯度： 98%
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