Taribavirin hydrochloride 是一种具有口服活性的肌苷-磷酸脱氢酶抑制剂，具有抗多种病毒的活性，特别是丙型肝炎病毒和流感病毒。Taribavirin hydrochloride 是利巴韦林前药，旨在集中在肝脏内以靶向 HCV 感染的肝细胞，同时最小化红细胞 (RBC) 内的分布和溶血性贫血的发展。
| 生物活性 |
Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin prodrug, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia. |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 体外研究 |
Taribavirin hydrochloride (0-2 μM; 24 hours) significantly induces MCF-7 cell death, recording half inhibitory effect (IC50) of 0.756 μM in MCF-7 cells. Cell Viability Assay
|
||||||||||||
| 分子式 |
C8H13N5O4.HCl
|
||||||||||||
| 分子量 |
279.68
|
||||||||||||
| CAS号 |
40372-00-7
|
||||||||||||
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
||||||||||||
| 储存方式 |
|
||||||||||||
| 临床试验 |
|
纯度： 98%
关注我们
获得KKL MED 最新资讯
客服小K 
客服小K
Data Sheet