Nemifitide diTFA - CAS:204992-09-6

您当前的位置：

Nemifitide diTFA (Synonyms:INN 00835 diTFA)

目录号 : KM8738 CAS No. : 204992-09-6 纯度 : 98%

Data Sheet 产品使用指南

Nemifitide diTFA (INN 00835 diTFA) 是一种合成的五肽抗抑郁药，具有迅速起效的潜力。Nemifitide diTFA 是黑色素细胞抑制因子 (MIF) 的肽类似物。Nemifitide diTFA 可以透过血脑屏障。

规格	价格	是否有货
5mg		In-stock
10mg		In-stock
50mg		In-stock
100mg	询价	In-stock
200mg	询价	In-stock

加入购物车大包装询价

Other Forms of Rapamycin:

(Tyr0)-Urocortin, rat In-stock
Stressin I In-stock
Suc-AAA-pNA In-stock
Perfluoropolyether carboxylic acid In-stock
Ala-D-γ-Glu-Lys-D-Ala-D-Ala In-stock

KKL Med 的所有产品和服务仅用于科学研究，不能被用于人体，兽医，我们也不向个人提供产品和服务。

生物活性

Nemifitide diTFA (INN 00835 diTFA) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. Nemifitide diTFA is a peptide analog of melanocyte-inhibiting factor (MIF). Nemifitide diTFA can cross the blood-brain barrier.

体外研究

Nemifitide diTFA (INN 00835 diTFA) and its active metabolite (M1) bind at micromolar concentrations to several receptors including the 5-HT_2A, 5-HT_2C, melanocortin MC4, MC5 and bombesin.

体内研究

Nemifitide diTFA (INN 00835 diTFA; 0.3 mg/kg; IP; daily; for 14 days) significantly increases swimming in the FSL rats after just 5 days of treatment and has long-lasting effect.
Nemifitide diTFA (0.0125-15.0 mg/kg) significantly increases swimming in the FSL rats at both low (0.025-0.3 mg/kg) and high (3.0-15.0 mg/kg) doses but not at intermediate (0.4-2.4 mg/kg) doses.

Animal Model:	Male Flinders Sensitive Line (FSL) rat weighing 280-320 g
Dosage:	0.3 mg/kg
Administration:	IP; daily; for 14 days
Result:	Significantly increased swimming in the FSL rats after just 5 days of treatment and had long-lasting effect.

分子式

C₃₃H₄₃N₁₀O₆F^.₂[C₂Ho₂F₃]

分子量

922.80

CAS号

204992-09-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Protect from light

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据

In Vitro:

H₂O : 250 mg/mL (270.91 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.0837 mL	5.4183 mL	10.8366 mL
5 mM	0.2167 mL	1.0837 mL	2.1673 mL
10 mM	0.1084 mL	0.5418 mL	1.0837 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

纯度： 98%