SDZ 224-015 是具有口服活性的、IL-1β 转化酶和 caspase-1 的抑制剂。SDZ 224-015 具有抗COVID-19的活性，靶向 Mpro (IC50 of 30 nM)。
| 生物活性 |
SDZ 224-015 is an orally active inhibitor of the interleukin-1 beta (IL-1β) converting enzyme and caspase-1. SDZ 224-015 possesses anti-COVID-19 activity, targeting M (IC50 of 30 nM). |
|---|---|
| 体内研究 |
SDZ 224-015 (0.3-300 μg/kg) potently reduces carrageenin-induced paw oedema.
|
| 分子式 |
C30H35Cl2N3O9
|
| 分子量 |
652.52
|
| CAS号 |
161511-45-1
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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