ω-Hydroxy-DEET 是一种驱虫剂 DEET 的主要代谢产物。ω-Hydroxy-DEET 具有抗增殖作用。DEET 是一种空间驱避剂和刺激性物质，通常用于防止与蚊子接触。
| 生物活性 |
ω-Hydroxy-DEET is a major metabolite of insect repellent N-N-diethyl-meta-toluamide (DEET). ω-Hydroxy-DEET has anti-proliferative effects. DEET is a spatial repellent and an irritant that commonly used to prevent contact with mosquitoes. |
|---|---|
| 体外研究 |
Hepatoma cell studies reveals that ω-Hydroxy-DEET (DHMB; 0.1-10 μg/mL; 48-72 hours) treatments decreases cellular proliferation. |
| 体内研究 |
The metabolite ω-Hydroxy-DEET (DHMB) is extensively distributed following intravenous and topical skin administration of DEET in rats. The ω-Hydroxy-DEET appeared to be the major metabolite for DEET. Repeated once-daily topical application for 30 days lead to higher concentrations of ω-Hydroxy-DEET in the liver.
|
| 分子式 |
C12H17NO2
|
| 分子量 |
207.27
|
| CAS号 |
72236-22-7
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
4°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) |
纯度： 98%
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