Sepimostat dimethanesulfonate (FUT-187) 通过拮抗 NR2B N-methyl-D-aspartate 受体发挥神经保护作用， 作用位点在NR2B 亚基的 Ifenprodil 结合位点。Sepimostat dimethanesulfonate 抑制 Ifenprodil 结合的 Ki 值为 27.7 µM。
| 生物活性 |
Sepimostat dimethanesulfonate (FUT-187) exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit. Sepimostat dimethanesulfonate inhibits the Ifenprodil binding with a Ki value of 27.7 µM. |
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| 体内研究 |
Sepimostat (1 to 100 nmol/eye, intravitreal injection) exhibits significant neuroprotective effect.
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| 分子式 |
C22H23N5O5S
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| 分子量 |
565.62
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| CAS号 |
103926-82-5
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
客服小K 
客服小K
Data Sheet
