KKL 顾客使用本产品发表的 13 篇科研文献

2-NBDG, a fluorescent D-glucose analog, is a fluorescent indicator for monitoring glucose uptake into living cells. Ex: 467 nm; Em 542 nm.

It has since been demonstrated in living mammalian cells that the uptake of 2-NBDG takes place through glucose transporters (GLUTs) in a concentration-, time- and temperature-dependent manner. A short-period application of 2-NBDG produced a remarkable increase in the fluorescence intensity in COS-1 cells over-expressing GLUT2, whereas the increase was barely detectable in mock-transfected cells. In mouse insulin-secreting clonal MIN6 cells, uptake was inhibited by cytochalasin B, a specific blocker for GLUTs, and by D-glucose in a dose-dependent manner.

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