PQM130
目录号 : KG12534
CAS No. : 2089415-51-8
纯度 : 98%
PQM130, a Feruloyl-Donepezil Hybrid compound with brain penatration, is a multitarget drug candidate against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity. PQM130 acts as a neuroprotective compound for anti-AD drug development.
PQM130 (0.5-1 mg/kg, i.p., daily for 10 days) treatment after the i.c.v. AβO injection reduces oxidative damage and neuroinflammation and induces cell survival and protein synthesis through the modulation of GSK3β and extracellular signal-regulated kinases (ERK1/2) . Animal Model: Adult male C57Bl/6 mice (9 weeks old, 25-30 g body weight) .
Other Forms of Rapamycin:
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| 分子式 |
C23H27NO4
|
| 分子量 |
381.46
|
| CAS号 |
2089415-51-8
|
| 储存方式 |
Store at -20°C
|
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Data Sheet
