S-(1,2-Dichlorovinyl)-Cysteine (hydrochloride)
目录号 : KG10660
CAS No. : 2508026-62-6
纯度 : >95%
S-(1,2-Dichlorovinyl)-cysteine (hydrochloride) is a nephrotoxin and metabolite of trichloroethylene. It is formed via a dichlorovinyl glutathione intermediate and its subsequent cleavage by dipeptidase. S-(1,2-Dichlorovinyl)-cysteine (hydrochloride) (1 mM) is cytotoxic to isolated human renal proximal tubule cells. It increases urine levels of N-acetyl-β-D-glucosaminidase, total protein, and glucose in rabbits when administered at a dose of 10 mg/kg. S-(1,2-Dichlorovinyl)-cysteine (hydrochloride) induces renal necrosis and lethality in rats (LD50s = 66-83 mg/kg).
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| 分子式 |
C5H7Cl2NO2S.HCl
|
| 分子量 |
252.5
|
| CAS号 |
2508026-62-6
|
| 储存方式 |
-20°C
|
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