Nepicastat
(Synonyms:5-(氨甲基)-1-((S)-5,7-二氟-1,2,3,4-四氢-2-萘)-4-咪唑啉-2-硫酮;内匹司他;奈匹卡司他;铈(III)6,6,7,7,8,8,8-七氟-2,2-二甲基-3,5-辛烷二酮;5-(氨甲基)-1-((S)-5,7-二氟-1,2,3,4-四氢-2-萘)-4-咪唑啉-2-硫酮,盐酸盐)
目录号 : KG10622
CAS No. : 173997-05-2
纯度 : 98%
Nepicastat (SYN117; RS-25560-197) is a dopamine beta-hydroxylase inhibitor with IC50 of 8.5 ± 0.8 and 9.0 ± 0.8 nM for bovine and human, respectively. IC50 value: 8.5/9.0 nM(bovine/human dopamine beta-hydroxylase)Dopamine beta-hydroxylase is an enzyme that catalyzes the conversion of dopamine to norepinephrine. Nepicastat (SYN117; RS-25560-197) has been studied as a possible treatment for congestive heart failure, and appears to be well tolerated as such.
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分子式 |
C14H15F2N3S
|
分子量 |
295.35
|
CAS号 |
173997-05-2
|
中文名称 |
5-(氨甲基)-1-((S)-5,7-二氟-1,2,3,4-四氢-2-萘)-4-咪唑啉-2-硫酮
|
储存方式 |
Store at -20°C
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