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TR antagonist 1 is a high-affinity thyroid hormone receptor (TR) antagonist with IC₅₀s of 36 and 22 nM for TRα and TRβ, respectively.

TR antagonist 1 displays high affinity for both thyroid hormone TRα and TRβ (IC₅₀=36 and 22 nM, respectively). TR antagonist 1 acts as a full antagonist in the TRAFR cell assay and the IC₅₀ 32 nM for both TRAFα1 and TRAFβ1.

TR antagonist 1 treatment lowers heart rate and shows a possible trend toward an increase of low-density lipoprotein cholesterol (LDL-C) in the cholesterol fed rat model.

Room temperature in continental US; may vary elsewhere.

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。