Immethridine (hydrobromide)
(Synonyms:4-(1H-咪唑-4-甲基)-吡啶二溴酸盐)
目录号 : KCM14888
CAS No. : 699020-93-4
纯度 : ≥98%
Immethridine is a potent histamine H receptor agonist (K = 0.85 nM). It is selective for histamine H over histamine H receptors (K = 245 nM). Immethridine inhibits cAMP-stimulated β-galactosidase transcription in SK-N-MC cells expressing human H receptors (EC = 0.18 nM) and induces a concentration-dependent decrease of the electrically induced twitch contraction in isolated guinea pig ileum. In vivo, immethridine (30 mg/kg, s.c.) inhibits hydrochloric acid-induced formation of gastric lesions in rats.
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分子式 |
C9H9N3.2HBr
|
分子量 |
159.18798
|
CAS号 |
699020-93-4
|
中文名称 |
4-(1H-咪唑-4-甲基)-吡啶二溴酸盐
|
储存方式 |
-20°C
|