4,5,6,7-Tetrabromobenzimidazole
(Synonyms:4,5,6,7 - 四溴苯并咪唑;羧基布洛芬)
目录号 : KCM14384
CAS No. : 577779-57-8
纯度 : ≥98%
Casein kinase 2 (CK2) is a constitutive protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis, and its activity is increased in many proliferating tissues and tumors. 4,5,6,7-Tetrabromobenzimidazole is a selective, ATP-competitive inhibitor of CK2 with K values ranging from 0.5-1 µM in rat liver, S. cerevisiae, C. tropicalis, and N. crassa. It is inactive against PKA and PKC and a relatively weak inhibitor of CK1 (K = 54.4-64.2 µM).
Other Forms of Rapamycin:
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| 分子式 |
|
| 分子量 |
433.7
|
| CAS号 |
577779-57-8
|
| 中文名称 |
羧基布洛芬
|
| 储存方式 |
| Powder |
-20°C |
3 years |
| |
4°C |
2 years |
| In solvent |
-80°C |
6 months |
| |
-20°C |
1 month |
|