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cis-Flupenthixol (hydrochloride) (Synonyms:盐酸氟哌噻吨;(Z)-4-[3-[2-(三氟甲基)-9H-硫杂蒽-9-亚基]丙基]-1-哌嗪乙醇二盐酸盐;顺式-(Z)-氟哌噻吨二盐酸盐;盐顺式酸氟哌噻吨;黛力新(盐酸氟哌噻吨+美利曲辛)合成技术转让;顺-（Z）-Flupentixoldihydrochloride;盐酸氟哌噻吨-;(Z)-4-[3-[2-(三氟甲基)-9H-噻吨-9-基]丙基]-1-哌嗪二盐酸盐)
目录号 : KCM14045 CAS No. : 51529-01-2 纯度 : ≥95%
Data Sheet SDS 产品使用指南
cis-Flupenthixol is a typical antipsychotic, a dopamine D receptor antagonist (K = 0.38 nM), and an inverse agonist at the serotonin (5-HT) receptor subtype 5-HT (K = 7 nM). In vivo, cis-flupenthixol (0.5 mg/kg, i.p.) reduces cocaine-induced locomotor activity and prevents development of conditioned place preferences for the immediate effects of intravenously administered cocaine without affecting development of conditioned place aversions in rats. cis-Flupenthixol also inhibits acid sphingomyelinase activity by 81.8% when used at a concentration of 10 mM.
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分子式
C23H25F3N2Os.2HCl
分子量
434.48
CAS号
51529-01-2
中文名称
盐酸氟哌噻吨
储存方式
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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