Ani 9
目录号 : KCM13494
CAS No. : 356102-14-2
纯度 : ≥98%
Ani 9 is an inhibitor of the calcium-activated chloride channel (CaCC) anoctamin 1 (ANO1) that blocks ATP-induced apical membrane chloride currents in ANO1-expressing Fischer rat thyroid (FRT) cells (IC = 77 nM). It is selective for ANO1 over ANO2 at 10 μM and the cystic fibrosis transmembrane conductance regulator (CFTR) and epithelial sodium channel (ENaC) at 30 μM. Ani 9 inhibits ATP-induced quenching of a fluorescent intracellular halide sensor in PC3 prostate cancer cells and Capan-1 pancreatic carcinoma cells in a concentration-dependent manner.
Other Forms of Rapamycin:
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分子式 |
C17H17ClN2O3
|
分子量 |
332.78126
|
CAS号 |
356102-14-2
|
中文名称 |
(4-Chloro-2-methylphenoxy)-[(2-methoxyphenyl)methylene]hydrazideAceticAcid
|
储存方式 |
-20°C
|