IKK2 Inhibitor VI
(Synonyms:3-(氨甲基)-5-甲基己酸)
目录号 : KCM13487
CAS No. : 354811-10-2
纯度 : ≥95%
Inhibitor of NF-κB kinase 2 (IKK2, also known as IKKβ) acts as part of an IKK complex in the canonical NF-κB pathway, phosphorylating inhibitors of NF-κB (IκBs) to initiate signaling. NF-κB signaling can also occur through a non-canonical, IKK/IκB-independent pathway. IKK2 Inhibitor VI is a potent, cell-permeable, reversible inhibitor of IKK2 (IC = 13 nM). It is used to evaluate the role of the canonical, IκB-dependent NF-κB signaling pathway in cellular responses.
Other Forms of Rapamycin:
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分子式 |
C12H11N3O2S
|
分子量 |
261.3
|
CAS号 |
354811-10-2
|
中文名称 |
3-(氨甲基)-5-甲基己酸
|
储存方式 |
-20°C
|