Garenoxacin (Synonyms:加雷沙星;1-环丙基-8-(二氟甲氧基)-7-[(1R)-1-甲基-2,3-二氢-1H-异吲哚-5-基]-4-氧代喹啉-3-羧酸;加雷沙星杂质)
目录号 : KCM12298 CAS No. : 194804-75-6 纯度 : ≥98%
Garenoxacin is a quinolone antibiotic. It is active against a variety of Gram-positive and Gram-negative bacteria (MICs = 0.025-6.25 and 0.0125-100 µg/ml, respectively). Garenoxacin inhibits E. coli DNA gyrase supercoiling and S. aureus topoisomerase IV decatenation activities (ICs = 0.17 and 2.19 mg/L, respectively). It is selective for S. aureus topoisomerase IV over human topoisomerase II (IC = 509.7 µg/L). Garenoxacin is efficacious against systemic quinolone-resistant S. aureus infection and pneumonia induced by the penicillin-resistant S. pneumoniae clinical isolate D-979 in mice (EDs = 0.0189 and 0.0278 mg/animal, respectively).
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5mg
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10mg
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分子式
C23H20F2N2O4
分子量
426.4127864
CAS号
194804-75-6
中文名称
加雷沙星
储存方式
-20°C
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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