Erastin2
目录号 : KCM11933
CAS No. : 1695533-44-8
纯度 : ≥98%
Erastin2 is a ferroptosis inducer and an inhibitor of the system x cystine/glutamate transporter. It inhibits glutamate release in CCF-STTG1 cells (IC = 0.0035 µM). It induces cell death in HAP1 cells when used at a concentration of 5 µM, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 or deferoxamine . Erastin2 also induces ferroptotic cell death in HT-1080 cells (EC = 0.15 µM), an effect that can be blocked by the reducing agent β-mercaptoethanol (EC = >20 µM). It increases lipid peroxidation in HT-1080 cells when used at a concentration of 1 µM.
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| 分子式 |
C36H35ClN4O4
|
| 分子量 |
623.14036
|
| CAS号 |
1695533-44-8
|
| 储存方式 |
-20°C
|
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