Gavestinel (sodium salt)
(Synonyms:4,6-二氯-3-[(1E)-3-氧代-3-(苯基氨基)-1-丙烯基]-1H-吲哚-2-羧酸单钠盐)
目录号 : KCM11624
CAS No. : 153436-38-5
纯度 : ≥98%
Gavestinel is an NMDA receptor antagonist. It selectively binds to the glycine site of the NMDA receptor over the glutamate binding site of NMDA, AMPA, or ionotropic kainate (GluK) receptors (Ks = 0.003, 10, 7.94, and 3.98 µM, respectively) and is selective for the NMDA receptor over a panel of 70 receptors (ICs = >10 µM for all). Gavestinel (0.03-0.35 µM) inhibits glutamate-induced increases in intracellular calcium levels in primary rat neonatal cerebral cortical neurons. It reduces infarct volume in a rat model of focal ischemia induced by middle cerebral artery occlusion (MCAO) when administered intravenously at a dose of 3 mg/kg.
Other Forms of Rapamycin:
KKL Med 的所有产品和服务仅用于科学研究，不能被用于人体，兽医，我们也不向个人提供产品和服务。
KKL 顾客使用本产品发表的 0 篇科研文献
暂无科研文献
| 分子式 |
C18H11Cl2N2O3.Na
|
| 分子量 |
374.19702
|
| CAS号 |
153436-38-5
|
| 储存方式 |
-20°C
|
客服小K 
客服小K
Data Sheet
