MK2 Inhibitor III - CAS:1186648-22-5

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MK2 Inhibitor III

目录号 : KCM10540 CAS No. : 1186648-22-5 纯度 : ≥95%

Data Sheet 产品使用指南

MAP kinase-activated protein kinase 2 (MAPKAP2, MK2) is a stress-activated serine/threonine protein kinase that is phosphorylated by p38 MAP kinase and is involved in diverse cellular functions with a central role in inflammation. MK2 inhibitor III is a potent, cell-permeable inhibitor of MK2 (IC = 8.5 nM). It less potently blocks MK3 and MK5 (ICs = 210 and 81 nM, respectively) and is weak or inactive against several other kinases, including other p38 MAP kinase targets. MK2 inhibitor III prevents LPS-induced synthesis of TNF-α in human monocyte-like U937 cells (IC = 4.4 µM).

规格	价格	是否有货	数量
500μg		In-stock
1mg		In-stock
5mg		In-stock

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分子式

C₂₁H₁₆N₄O^.H₂O

分子量

358.4

CAS号

1186648-22-5

中文名称

MK-2 Inhibitor III

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

纯度： ≥95%

Data Sheet

产品使用指南

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