Gardiquimod
(Synonyms:嘎德莫特;4-氨基-2-[(乙基氨基)甲基]-alpha,alpha-二甲基-1H-咪唑并[4,5-c]喹啉-1-乙醇)
目录号 : KCM10076
CAS No. : 1020412-43-4
纯度 : ≥95%
Gardiquimod is an agonist of human toll-like receptor 7 (TLR7), but not human TLR8, although it activates both porcine TLR7 and TLR8. At 0.5 to 2 µg/ml, it enhances the immunosuppressive activity of T regulatory cells. Gardiquimod is effective as a mucosal adjuvant for Norwalk virus-like particles and inhibits infection of macrophages and T cells by HIV-1. It inhibits proliferation and migration while inducing apoptosis in pancreatic cancer cells in vitro.
Other Forms of Rapamycin:
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分子式 |
C17H23N5O
|
分子量 |
313.4
|
CAS号 |
1020412-43-4
|
中文名称 |
嘎德莫特
|
储存方式 |
-20°C
|