rac-BHFF has anxiolytic-like properties in stress-induced hyperthermia (SIH) in mice.
rac-BHFF (3, 10, 30 and 100 mg/kg, p.o.) reverses SIH and high significance was reached for 100 mg kg−1 (P<0.001).
Animal Model: |
Male NMRI mice (20-25 g). |
Dosage: |
3, 10, 30 or 100 mg/kg. |
Administration: |
P.O.. |
Result: |
Significantly increased the LRR effects of a subthreshold dose of baclofen at doses of 3 mg/kg and above. |