Cystathionine-γ-lyase-IN-1 (compound 2a) completely abrogates L-cysteine-induced vasorelaxation at a concentration of 100 μM.
Cystathionine-γ-lyase-IN-1 (100 μM; 30 minutes) significantly inhibits the increased H2S production stimulated by L-Cys in mouse aorta homogenates.