FSL-1
目录号 : KM17582 CAS No. : 322455-70-9

FSL-1 是细菌衍生的一种 Toll 样受体 2/6 (TLR2/6) 激动剂,可增强对HSV-2感染的抵抗力。

规格 价格 是否有货 数量
1mg
In-stock
5mg
In-stock

Other Forms of Rapamycin:

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生物活性

FSL-1, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection.

体外研究

FSL-1 significantly reduces HSV-2 replication in vitro. FSL-1 reduces HSV-2 replication in human vaginal epithelial cells (EC).
FSL-1 induces significant resistance to experimental genital HSV-2 infection through elaboration of a specific cytokine response profile.
FSL-1 enhances phagocytosis of bacteria by macrophages through a Toll-like receptor 2-mediated signalling pathway.

Cell Viability Assay

Cell Line: V11I, V12I or V19I immortalized human vaginal EC
Concentration: 6 μg or 0.1 μg
Incubation Time: Added at 24, 6 or just prior to HSV-2 inoculation (10pfu/well)
Result: The 6 μg does produced significant reductions when delivered at 24 or 6 h prior to HSV-2 inoculation. The 0.1 μg dose produced reduced HSV-2 replication at 24 or 6 h prior to viral challenge.
分子式
C84H140N14O18S
分子量
1666.16
CAS号
322455-70-9
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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