ATP disodium trihydrate (Synonyms:腺苷三磷酸二钠三水合物; Adenosine-5'-triphosphate disodium trihydrate)
目录号 : KM17431 CAS No. : 51963-61-2 纯度 : 98%

ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) 是体内能量储存和代谢的重要物质,为代谢提供能量,同时在细胞中作为辅酶发挥作用。ATP disodium trihydrate 是免疫和炎症中重要的内源性信号分子。

规格 价格 是否有货 数量
100mg
In-stock
500mg
In-stock
1g 询价 In-stock
5g 询价 In-stock
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生物活性

ATP disodium trihydrate (Adenosine 5'-triphosphate disodium trihydrate) is a central component of energy storage and metabolism in vivo. ATP disodium trihydrate provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium trihydrate is an important endogenous signaling molecule in immunity and inflammation.

体外研究

ATP disodium trihydrate (5 mM; 1 hour) co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.
ATP disodium trihydrate (2 mM; 0.5-24 hours) induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner.
ATP disodium trihydrate promotes neutrophil chemotaxis in vitro.

体内研究

ATP disodium trihydrate (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.
ATP disodium trihydrate induces the secretion of IL-1β, KC and MIP-2 and neutrophils recruitment in vivo.

Animal Model: Four-week-old Kunming mice (18-22 g)
Dosage: 50 mg/kg
Administration: Intraperitoneal injection, before bacterial (E. coli) challenge
Result: Protected mice from bacterial infection.
分子式
C10H14N5Na2O13P3
分子量
605.19
CAS号
51963-61-2
中文名称
腺苷三磷酸二钠三水合物
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
In Vitro: 

H2O : 250 mg/mL (413.09 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.6524 mL 8.2619 mL 16.5237 mL
5 mM 0.3305 mL 1.6524 mL 3.3047 mL
10 mM 0.1652 mL 0.8262 mL 1.6524 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

临床试验
科研文献
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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