CTTHWGFTLC, CYCLIC TFA 是一种基质金属蛋白酶 MMP-2 和 MMP-9 的环肽抑制剂。对 MMP-9 的 IC50 约为 8 μM。
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CTTHWGFTLC, CYCLIC TFA is a cyclic peptide inhibitor for matrix metalloproteinases MMP-2 and MMP-9. The IC50 value for MMP-9 is ~8 μM.
CTTHWGFTLC, CYCLIC TFA inhibits endothelial and tumor cell migration in vitro.
CTTHWGFTLC, CYCLIC TFA inhibits tumor progression in vivo, in mouse models.
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