Revexepride 是一种高度选择性的 5-HT4 receptor 激动剂，也是潜在的 CYP3A4 enzyme 诱导剂，可用于研究胃食管返流疾病。
| 生物活性 |
Revexepride is a highly selective 5-HT4 receptor agonist, and a potential inducer of CYP3A4 enzyme, used for the treatment of gastroesophageal reflux disease. |
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| 体外研究 |
The human CYP isoenzymes are involved in the metabolism of revexepride, which is mainly metabolized in vitro in humans by CYP3A4 (99.9%) with a minor contribution of CYP2D6 (0.1%). Revexepride exhibits direct inhibition of human CYP3A4 in vitro with IC50 values of 16-49 μM. |
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| 分子式 |
C21H32ClN3O4
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| 分子量 |
425.95
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| CAS号 |
219984-49-3
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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