CCX354 是一种有效的 CCR1 拮抗剂,具有抗炎活性。
CCX354 is an antagonist of CCR1, with anti-inflammatory activity.
CCX354 shows potent activities in the chemotaxis assay, with IC50 < 100 nM.
In vivo, CCX354 has in vivo anti-inflammatory activity and has superior pharmacokinetic properties.
Room temperature in continental US; may vary elsewhere.