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Testosterone undecanoate (Synonyms:Testosterone undecylate)
目录号 : KM16134 CAS No. : 5949-44-0 纯度 : ≥98%

Testosterone undecanoate是睾酮酯,用做男性节育。

规格 价格 是否有货 数量
100mg
In-stock
1g
In-stock
5g
In-stock
10g 询价 In-stock
50g 询价 In-stock

Other Forms of Rapamycin:

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生物活性

Testosterone undecanoate is an ester of testosterone; used in androgen replacement therapy primarily for the treatment of male hypogonadism, and is currently under research for use as a male contraceptive.

体外研究

Cell Viability Assay

Cell Line: The MCF-7 [ER+, progesterone receptor (PR)+ and AR+] breast cancer cells
Concentration: 20 and 200 μg/mL
Incubation Time: 0, 24, 48 and 72 hours
Result: Following 48 h of treatment, the Testosterone undecanoate and all drug combination groups had significantly fewer viable cells than those of the Anastrozole-treated group.
Following treating for 72 h, the cellular proliferation inhibition rates in all groups were higher than at 0-24 h and the results revealed that the drug combination groups eradicated more cancer cells than the Anastrozole-treated group.

Western Blot Analysis

Cell Line: MCF-7 cells
Concentration: 0.1 μg/mL Anastrozole + 20 or 200 μg/mL Testosterone undecanoate and 0.01 μg/mL Anastrozole + 20 or 200 μg/mL Testosterone undecanoate
Incubation Time: 24 and 48 hours
Result: The AR protein expression levels were significantly reduced in the 0.1 μg/mL + 20 μg/mL combined treatment group, compared with those of the 20 μg/mL Testosterone undecanoate-treated group.
The AR expression levels in the 0.1 μg/mL + 200 μg/mL experimental group were significantly lower than those is the 200 μg/mL Testosterone undecanoate-treated group.
分子式
C30H48O3
分子量
456.70
CAS号
5949-44-0
中文名称
十一酸睾酮;十一酸睾丸素;十一烷酸睾酮;十一酸睾丸酮
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

DMSO : 10 mg/mL (21.90 mM; Need ultrasonic and warming)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.1896 mL 10.9481 mL 21.8962 mL
5 mM 0.4379 mL 2.1896 mL 4.3792 mL
10 mM 0.2190 mL 1.0948 mL 2.1896 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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