USP7-IN-1 是一种选择性的，可逆的泛素蛋白特异性蛋白酶 (USP7) 抑制剂，IC50 值为 77 μM，可用于癌症研究。
| 生物活性 |
USP7-IN-1 is a selective and reversible inhibitor of ubiquitin-specific protease 7 (USP7), with an IC50 of 77 μM, and can be used for the research of cancer. |
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| 体外研究 |
USP7-IN-1 (Example 2) is a selective and reversible inhibitor of USP7, with an IC50 of 77 μM, and shows no inhibition of USP8, USP5, Uch-L1, Uch-L3 or caspase 3. USP7-IN-1 inhibits the proliferation of HCT116 cells, with a GI50 of 67 μM. |
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| 分子式 |
C23H24ClN3O3
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| 分子量 |
425.91
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| CAS号 |
1381291-36-6
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 溶解性数据 |
In Vitro:
DMSO : ≥ 40 mg/mL (93.92 mM) * "≥" means soluble, but saturation unknown. 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 |
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| 科研文献 |
纯度： 98%
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