Atrial natriuretic factor (1-28) (human, porcine) 是 pro-opiomelanocortin (POMC) mRNA 的强效抑制因子和βEP-LI释放的弱抑制因子。
| 生物活性 |
Atrial natriuretic factor (1-28) (human, porcine) is a potent suppressor of pro-opiomelanocortin (POMC) mRNA but a weak inhibitor of βEP-LI release. |
|---|---|
| 体外研究 |
ANF-(1-28) markedly increaseS guanosine 3',5'-cyclic monophosphate (cGMP) from 1.3 +/- 0.3 to 106 +/- 22 pmol cGMP/10(6) cells [50% effective dosage (ED50) = 1.2 nM]. |
| 体内研究 |
ANF-(1-28) (0.5 µg/kg/min) infusion attenuates the rise in plasma creatinine levels by approximately 50% on each day of the study.
|
| 分子式 |
C127H205N45O39S3
|
| 分子量 |
3080.46
|
| CAS号 |
91917-63-4
|
| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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