L-Carnitine (Synonyms:左旋肉碱; Levocarnitine)
目录号 : KM13681 CAS No. : 541-15-1 纯度 : ≥98%

L-carnitine (Levocarnitine) 是一种参与脂肪酸代谢的内源性分子,在人体内以赖氨酸和蛋氨酸为底物进行生物合成。L-Carnitine 通过 β-氧化作用将长链脂肪酰辅酶A转运到线粒体降解。L-Carnitine 可以改善许多先天性代谢错误的代谢失衡。

规格 价格 是否有货 数量
500mg
In-stock
5g
In-stock
10g
In-stock
50g 询价 In-stock

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生物活性

L-Carnitine (Levocarnitine) is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism.

体外研究

L-carnitine increases β oxidation and the resultant acetyl-coA joins the Krebs's cycle resulting in burning of fats and increases energy production, hence it increases the utilization of cellular fatty acids, and removal of abnormal fat on cellular membrane. It also acts as a fat burner by optimizing fat oxidation and consequently reducing its availability for storage.

体内研究

L-carnitine reduces HFD induced lipid perioxidation and alteration of antioxidant biomarker in rats hepatic tissue.

分子式
C7H15NO3
分子量
161.20
CAS号
541-15-1
中文名称
左旋肉碱
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

溶解性数据
In Vitro: 

H2O : ≥ 50 mg/mL (310.17 mM)

* "≥" means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 6.2035 mL 31.0174 mL 62.0347 mL
5 mM 1.2407 mL 6.2035 mL 12.4069 mL
10 mM 0.6203 mL 3.1017 mL 6.2035 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (stored under nitrogen)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

临床试验
科研文献
The molarity calculator equation
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2
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