Sultopride hydrochloride (LIN-1418 hydrochloride) 是多巴胺 D2 受体的选择性拮抗剂。
| 生物活性 |
Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor. |
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| 体内研究 |
Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor. DOPAC and HVA levels in the striatum, the nucleus accumbens and the medial prefrontal cortex are higher in the rats treated with Sultopride hydrochloride and sulpiride than those of the controls. In the striatum, DOPAC and HVA levels are higher in the Sultopride hydrochloride-treated rats than the sulpiride-treated rats (p<0.05). In the nucleus accumbens, DOPAC levels are higher in the Sultopride hydrochloride-treated rats than sulpiride treated rats (p<0.05). In the Sultopride hydrochloride-treated rats, DOPAC and HVA levels are higher in the striatum or in the nucleus accumbens than in the medial prefrontal cortex (p<0.05).
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| 分子式 |
C17H26N2O4S.HCl
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| 分子量 |
390.93
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| CAS号 |
23694-17-9
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| 中文名称 |
盐酸舒必利
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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| 溶解性数据 |
In Vitro:
DMSO : 50 mg/mL (127.90 mM; Need ultrasonic) H2O : 50 mg/mL (127.90 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：
——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；
以下溶剂前显示的百
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| 科研文献 |
纯度： 98%
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Data Sheet
