Hydroxypyruvic acid (β-Hydroxypyruvic acid) 是甘氨酸、丝氨酸和苏氨酸代谢的中间产物 (intermediate)。Hydroxypyruvic acid 是丝氨酸-丙酮酸氨基转移酶和乙醛酸还原酶/羟基丙酮酸还原酶的底物 (substrate)。Hydroxypyruvic acid 参与了二甲基甘氨酸脱氢酶缺乏症的代谢紊乱途径。
| 生物活性 |
Hydroxypyruvic acid (β-Hydroxypyruvic acid) is an intermediate in the metabolism of glycine, serine and threonine. Hydroxypyruvic acid is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. Hydroxypyruvic acid is involved in the metabolic disorder which is the dimethylglycine dehydrogenase deficiency pathway. |
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| 体内研究 |
Hydroxypyruvic acid (intravenous injection; 100 mg/ml; slowly over 10 min) increases the 5-h urinary oxalate and glycolate excretion to 0.68% (6.56 μmol) and 0.53% (5.10 μmol) in control rats, in addition, it increases to 2.43% (23.36 μmol) and 0.79% (7.59 μmol) of the dose in the vitamin-B6-deficient rats.
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| 分子式 |
C3H4O4
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| 分子量 |
104.06
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| CAS号 |
1113-60-6
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| 中文名称 |
羟基丙酮酸
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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