113-O12B - CAS:2803699-72-9

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113-O12B

目录号 : KG12975 CAS No. : 2803699-72-9 纯度 : >95%

Data Sheet 产品使用指南

113-O12B is a disulfide bond-containing ionizable cationic lipidoid. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA. Subcutaneous administration of LNPs containing 113-O12B and encapsulating an mRNA reporter accumulate specifically in mouse lymph nodes. LNPs containing 113-O12B and encapsulating mRNA encoding ovalbumin reduce tumor growth and increase the number of tumoral CD8+ T cells, M1-like macrophages, and activated dendritic cells in an ovalbumin-expressing B16/F10 murine melanoma model.

规格	价格	是否有货	数量
5mg		In-stock
10mg		In-stock
25mg		In-stock

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生物活性	113-O12B is a disulfide bond-containing ionizable cationic lipidoid. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA. Subcutaneous administration of LNPs containing 113-O12B and encapsulating an mRNA reporter accumulate specifically in mouse lymph nodes. LNPs containing 113-O12B and encapsulating mRNA encoding ovalbumin reduce tumor growth and increase the number of tumoral CD8+ T cells, M1-like macrophages, and activated dendritic cells in an ovalbumin-expressing B16/F10 murine melanoma model.
分子式	C₅₇H₁₁₁N₃O₈S₈
分子量	1223
CAS号	2803699-72-9
中文名称	INNYA-2282403
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Store at -20°C