L-Aspartic acid 13C 是13C 标记的L-Aspartic acid。L-Aspartic acid 是一种氨基酸，被证明是一种结肠特异性药物输送的前体药物。
| 生物活性 |
L-Aspartic acid 13C is a 13C labeled L-Aspartic acid. L-Aspartic acid is is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly. |
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| 体外研究 |
L-Aspartic acid is shown to be a suitable prodrug for colon-specific drug deliverly. L-[3H]Asp remaining in the brain at 5 min is increased by 206 and 178% by preadministration of 100 mM L-Aspartic acid and 100 mM L-Glu, respectively, whereas 100 mM D-Asp does not affect L-[3H]Asp efflux transport. That value for L-[3H]Glu at 20 min is increased by 145 and 156% by coadministration with 100 mM L-Aspartic acid and 100 mM L-Glu, respectively, but not by D-Asp. It is interesting that the apparent efflux rate of L-Aspartic acid across the BBB is sevenfold faster than that of L-Glu. |
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| 分子式 |
C313CH7NO4
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| 分子量 |
134.1
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| CAS号 |
81201-97-0
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| 运输条件 |
Room temperature in continental US; may vary elsewhere. |
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| 储存方式 |
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纯度： ≥98%
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