Oxolinic acid - CAS:14698-29-4

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Oxolinic acid (Synonyms:恶喹酸)

目录号 : KM16143 CAS No. : 14698-29-4 纯度 : 98%

Data Sheet 产品使用指南

Oxolinic acid 是一种抗生素 (antibiotic) ，对革兰氏阴性菌和革兰氏阳性菌均有效。Oxolinic acid 可用于急性和慢性尿路感染的研究。Oxolinic acid 是一种 DNA/RNA 合成 (DNA/RNA synthesis) 抑制剂。Oxolinic acid 是一种多巴胺摄取抑制剂，能刺激小鼠的活跃过度。

规格	价格	是否有货
500mg		In-stock
1g		In-stock
5g	询价	In-stock
10g	询价	In-stock

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生物活性

Oxolinic acid is an antibiotic against both Gram-negative and Gram-positive bacteria. Oxolinic acid can be used for the research of acute and chronic urinary tract infections. Oxolinic acid is a DNA/RNA synthesis inhibitor. Oxolinic acid acts a dopamine uptake inhibitor and stimulants locomotor effect in mice.

体外研究

Oxolinic acid (2-5 ug/mL) inhibits 115 strains of E. coli.
Oxolinic acid (0-31 ug/mL) inhibits 94 % of the 44 strains of Proteus mirabilis .
Oxolinic acid (>5 ug/mL) inhibits all strains of Strept. Faecalis.
Oxolinic acid (>2 ug/mL) causes chromosomal DNA supercoiling to decrease in the two wild-type E. coli K-12 strains tested, DM4100 and NI747.
Oxolinic acid reduces chromosomal DNA supercoiling and inhibits RNA synthesis in E. coli.

体内研究

Oxolinic acid (32 mg/kg; i.p.) induces hyperactivity in mice.

Animal Model:	Male Swiss albino CD1 mice (22-25 g)
Dosage:	16 mg/kg, 32 mg/kg, 64 mg/kg, 128 mg/kg
Administration:	Intraperitoneal injection
Result:	Stimulated the horizontal activity of mice, culminated at the 32 mg/kg dose but disappeared at the highest tested dose, 128 mg/kg.

分子式

C₁₃H₁₁NO₅

分子量

261.23

CAS号

14698-29-4

中文名称

恶喹酸；奥索利酸

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

DMSO : 1 mg/mL (3.83 mM; Need ultrasonic)

H₂O : < 0.1 mg/mL (insoluble)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	3.8280 mL	19.1402 mL	38.2804 mL
5 mM	---	---	---
10 mM	---	---	---

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

科研文献

•Chemosphere. 2019 Jun;225:378-387.

纯度： 98%

Data Sheet

产品使用指南

摩尔计算器
稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量

浓度

体积

分子量*

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度

体积

浓度

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Other Forms of Rapamycin:

KKL 顾客使用本产品发表的 1 篇科研文献

The molarity calculator equation

The dilution calculator equation